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HBsAg is produced in recombinant yeast cells. A portion of the hepatitis B virus gene, coding for HBsAg, is cloned into yeast, and the vaccine for hepatitis B is produced from cultures of this recombinant yeast strain according to methods developed in the Merck Research Laboratories. The antigen is harvested and purified from fermentation cultures of a recombinant strain of the yeast Saccharomyces cerevisiae containing the gene for the adw subtype of HBsAg. The fermentation process involves growth of Saccharomyces cerevisiae on a complex fermentation medium which consists of an extract of yeast, soy peptone, dextrose, amino acids and mineral salts.8. Stainer DW, et al. A simple chemically defined medium for the production of phase 1 Bordetella pertussis. J Gen Microbiol 1971;63:211-20.SIDE EFFECTS: Injection site reactions (such as pain, redness, irritation) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: signs of low potassium level in the blood (such as muscle cramps, weakness, irregular heartbeat). This medication can cause low blood sugar (hypoglycemia). This may occur if you do not consume enough calories from food or if you do unusually heavy exercise. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drink fruit juice or non-diet soda. Tell your doctor immediately about the reaction and the use of this product. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals. Check with your doctor or pharmacist to find out what you should do if you miss a meal. Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor immediately. Your dosage may need to be increased. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, fast heartbeat, sweating, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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Each 10.6-g canister (44 mcg) and each 12-g canister (110 and 220 mcg) provides 120 inhalations.

NOTES: Do not share this medication with others. Laboratory and/or medical tests (such as kidney function, bicarbonate level, complete blood count) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.some medicines for treating depression or mood problems (amoxapine, maprotiline, fluoxetine, fluvoxamine, nefazodone, pimozide, phenothiazines, tricyclic antidepressants)Tell your doctor if you are taking any medicines, including those bought over-the-counter and herbal medicines, before you start treatment with Diclofenac Sodium EC. Similarly, check with your doctor or pharmacist before you take any new medicines while you are taking Diclofenac Sodium EC. Diclofenac Sodium EC may increase the blood levels of the following medicines: - lithium - digoxin - methotrexate. People taking Diclofenac Sodium EC with any of the above should be closely monitored by their doctor. There may be an increased risk of bleeding if Diclofenac Sodium EC is taken with blood-thinning or anti-clotting medicines (anticoagulants) such as warfarin. People taking Diclofenac Sodium EC with an anticoagulant should be closely monitored by their doctor. There may be an increased risk of side effects such as stomach irritation if Diclofenac Sodium EC is taken with corticosteroids such as prednisolone. Diclofenac Sodium EC should not be taken with any other NSAID, eg ibuprofen, as this increases the risk of side effects, particularly on the gut. Ciclosporin may increase the blood level of Diclofenac Sodium EC, and your doctor may prescribe a lower than normal dose of diclofenac if you are taking ciclosporin. There may be an increased risk of side effects on the kidneys if Diclofenac Sodium EC is taken with any of the following medicines: - ciclosporin - ACE inhibitors, eg enalapril - diuretics, eg frusemide (furosemide). Diclofenac Sodium EC may reduce the blood pressure lowering effects of diuretics such as frusemide (furosemide). There may potentially be an increased risk of seizures if Diclofenac Sodium EC is taken together with quinolone antibiotics such as ciprofloxacin. Uncommon (0.1% to 1%): Hypersensitivity

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Before taking levofloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolone antibiotics (such as ciprofloxacin, moxifloxacin, ofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Analysis of a 3 mm stone, eliminated by a 47-year-old HIV-1-infected male patient, showed a stone consisting of 60% efavirenz (the active ingredient contained in Sustiva) metabolites.[Ref]

Reported infections include:

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Special precautions of Naprosyn if you are pregnant or breastfeeding Fluoroquinolones, including LEVAQUIN, may exacerbate muscle weakness in persons with myasthenia gravis. Avoid LEVAQUIN in patients with a known history of myasthenia gravis [See WARNINGS AND PRECAUTIONS].Cyclosporine (Neoral, Sandimmune)

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