Tadalafil, sildenafil, and vardenafil all act by inhibiting the PDE5 enzyme. These drugs also inhibit other PDE enzymes. Sildenafil and vardenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil.[7] Some sildenafil users see a bluish tinge and have a heightened sensitivity to light because of PDE6 inhibition.[8] Sildenafil and vardenafil also inhibit PDE1 more than tadalafil.[7] PDE1 is found in the brain, heart, and vascular smooth muscle.[7] It is thought that the inhibition of PDE1 by sildenafil and vardenafil leads to vasodilation, flushing, and tachycardia.[7] Tadalafil inhibits PDE11 more than sildenafil or vardenafil.[7] PDE11 is expressed in skeletal muscle, the prostate, the liver, the kidney, the pituitary gland, and the testes.[7] The effects on the body of inhibiting PDE11 are not known.[7] viagra directions ?itching or burning during urination
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2.5 mg Cialis how long does viagra 50 mg last The specified medical conditions are diabetes, multiple sclerosis, Parkinson's disease, poliomyelitis, prostate cancer, an operation to remove the prostate gland (prostatectomy), radical pelvic surgery, renal failure treated by dialysis or transplant, severe pelvic injury, single gene neurological disease, spinal cord injury and spina bifida.Take 1 Levitra tablet about 1 hour (60 minutes) before sexual activity. Some form of sexual stimulation is needed for an erection to happen with Levitra. Levitra may be taken with or without meals.In these patients, the recommended dose is 5mg taken once a day at approximately the same time of day. The dose may be decreased to 2.5mg once a day based on individual tolerability.
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Following a single oral dose of 20 mg vardenafil in healthy volunteers, a mean of 0.00018% of the administered dose was obtained in semen 1.5 hours after dosing.Be careful driving or operating machinery until you know how CIALIS affects you.
how to take cialis 20mg Viagra puede ayudarlo a tener una erección cuando tenga estimulación sexual. La erección no ocurrirá solamente porque toma la pastilla. Siga las instrucciones de su médico.Placebo-subtracted Vardenafil 20 mg
42. Egan R, Pomeranz H "Sildenafil (Viagra) associated anterior ischemic optic neuropathy." Arch Ophthalmol 118 (2000): 291-2Do not take CIALIS:Patients with resting hypotension (BP <90/50 mmHg) or hypertension (BP >170/110 mmHg);
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